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| ID | Swiss Acc | Gene Name | Alias | Description | 8995 | Q9UNG2 | TNFSF18 | TL6; AITRL; GITRL; hGITRL | tumor necrosis factor (ligand) superfamily, member 18 |
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| [more aliases] |
| Function | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. |
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| Associations | TCM-Gene | TCM-Gene-Disease |
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| Gene Ontology | GO:0007267 cell-cell signaling GO:0005164 tumor necrosis factor receptor binding GO:0016021 integral to membrane GO:0016020 membrane GO:0005102 receptor binding GO:0006916 anti-apoptosis GO:0005615 extracellular space GO:0007165 signal transduction GO:0006955 immune response |
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Database cross references
| STITCH | TNFSF18 |
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Integrated protein interaction and pathway information
| Interacting Partners (HPRD) | Experiment |
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| TNFRSF18 | in vivo |
| Pathway (KEGG) | [Cytokine-cytokine receptor interaction] |
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