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ID | Swiss Acc | Gene Name | Alias | Description | 84957 | Q969Z4 | TNFRSF19L | RELT; FLJ14993 | tumor necrosis factor receptor superfamily, member 19-like |
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[more aliases] |
Function | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. |
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Associations | TCM-Gene | TCM-Gene-Disease |
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Gene Ontology | GO:0016020 membrane GO:0016021 integral to membrane GO:0004872 receptor activity |
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Database cross references
STITCH | TNFRSF19L |
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Integrated protein interaction and pathway information
Interacting Partners (HPRD) | Experiment |
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STK39 | in vitro;in vivo;yeast 2-hybrid |
- | in vivo |
Pathway (KEGG) | [Cytokine-cytokine receptor interaction] |
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