IDSwiss AccGene NameAliasDescription
84957Q969Z4TNFRSF19LRELT; FLJ14993tumor necrosis factor receptor superfamily, member 19-like
[more aliases]
FunctionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.

AssociationsTCM-GeneTCM-Gene-Disease

Gene OntologyGO:0016020 membrane
GO:0016021 integral to membrane
GO:0004872 receptor activity

Database cross references

STITCHTNFRSF19L

Integrated protein interaction and pathway information

Interacting Partners (HPRD)Experiment
STK39in vitro;in vivo;yeast 2-hybrid
-in vivo

Pathway (KEGG)[Cytokine-cytokine receptor interaction]


© 2008 National Taiwan Univerisity, Taipei, Taiwan