TCMGeneDIT: A Database of Traditional Chinese Medicine, Gene and Disease Infomation from Text Mining

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ID	Swiss Acc	Gene Name	Alias	Description
84957	Q969Z4	TNFRSF19L	RELT; FLJ14993	tumor necrosis factor receptor superfamily, member 19-like

[more aliases]

Function	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.

Function

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.

Associations	TCM-Gene	TCM-Gene-Disease

Gene Ontology	GO:0016020 membrane GO:0016021 integral to membrane GO:0004872 receptor activity

Database cross references

STITCH	TNFRSF19L

Integrated protein interaction and pathway information

Interacting Partners (HPRD)	Experiment
STK39	in vitro;in vivo;yeast 2-hybrid
-	in vivo

Pathway (KEGG)	[Cytokine-cytokine receptor interaction]