IDSwiss AccGene NameAliasDescription
7127Q03169TNFAIP2B94tumor necrosis factor, alpha-induced protein 2
[more aliases]
FunctionThis gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may be a retinoic acid target gene in acute promyelocytic leukemia.


Gene OntologyGO:0001525 angiogenesis
GO:0030154 cell differentiation
GO:0005615 extracellular space

Database cross references


Integrated protein interaction and pathway information

Pathway (NetPath)PubMedRegulationExperiment
IL-115336943 UpregulationMicroarray
TGF-beta Receptor14726474 DownregulationMicroarray
TNF-alpha15722553 DownregulationMicroarray

© 2008 National Taiwan Univerisity, Taipei, Taiwan