IDSwiss AccGene NameAliasDescription
23Q8NE71ABCF1ABC27; ABC50ATP-binding cassette, sub-family F (GCN20), member 1
[more aliases]
FunctionThe protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process.


Gene OntologyGO:0006412 protein biosynthesis
GO:0008135 translation factor activity, nucleic acid binding
GO:0006954 inflammatory response
GO:0042626 ATPase activity, coupled to transmembrane movement of substances
GO:0000166 nucleotide binding
GO:0016887 ATPase activity
GO:0005524 ATP binding

Database cross references


Integrated protein interaction and pathway information

Interacting Partners (HPRD)Experiment
ITGB4BPyeast 2-hybrid

Interacting Partner (IntAct)Interaction typeDetection method
ITGB3BP physical interaction two hybrid pooling
PINX1 physical interaction anti bait coip
PRKAB1 physical interaction anti bait coip
LYAR physical interaction anti bait coip

© 2008 National Taiwan Univerisity, Taipei, Taiwan