IDSwiss AccGene NameAliasDescription
1798Q9H3H5DPAGT1GPT; ALG7; DGPT; G1PT; UAGT; UGAT; DPAGT; CDG-Ij; DPAGT2; D11S366dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
[more aliases]
FunctionThe protein encoded by this gene is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. This enzyme belongs to the glycosyltransferase family 4. This protein is an integral membrane protein of the endoplasmic reticulum. The congenital disorder of glycosylation type Ij is caused by mutation in the gene encoding this enzyme. Alternatively spliced transcript variants encoding different isoforms have been identified.

AssociationsTCM-GeneTCM-Gene-Disease

Gene OntologyGO:0003975 UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity
GO:0016757 transferase activity, transferring glycosyl groups
GO:0005783 endoplasmic reticulum
GO:0016020 membrane
GO:0016021 integral to membrane
GO:0006629 lipid metabolism

Database cross references

STITCHDPAGT1

Integrated protein interaction and pathway information

Pathway (KEGG)[N-Glycan biosynthesis] [Glycan structures - biosynthesis 1]


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