IDSwiss AccGene NameAliasDescription
10578P22749GNLY519; LAG2; NKG5; LAG-2; D2S69E; TLA519; lymphokinegranulysin
[more aliases]
FunctionGranulysin is a protein present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells. Granulysin is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. Granulysin has antimicrobial activity against M. tuberculosis and other organisms. Granulysin is alternatively spliced, resulting in the NKG5 and 519 transcripts.


Gene OntologyGO:0042742 defense response to bacteria
GO:0006968 cellular defense response
GO:0050832 defense response to fungi
GO:0006805 xenobiotic metabolism
GO:0005615 extracellular space

Database cross references


Integrated protein interaction and pathway information

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