IDSwiss AccGene NameAliasDescription
920P01730CD4CD4mutCD4 antigen (p55)

Other aliasesCD4; CD 4; CD-4; CD4mut; CD 4 mut; CD4 molecule; CD 4 molecule; CD4 antigen (p55); CD 4 antigen (p 55); T-cell surface antigen T4/Leu3; T-cell surface antigen T4/Leu-3; T-cell surface antigen T4/Leu 3; T-cell surface antigen T 4/ Leu-3; T-cell surface antigen T 4/ Leu 3; T-cell surface glycoprotein CD4 precursor; T-cell surface glycoprotein CD 4 precursor

FunctionInformation is not available.


Gene OntologyGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0019901 protein kinase binding
GO:0005201 extracellular matrix structural constituent
GO:0016021 integral to membrane
GO:0005886 plasma membrane
GO:0001948 glycoprotein binding
GO:0000747 conjugation with cellular fusion
GO:0030217 T cell differentiation
GO:0042289 MHC class II protein binding
GO:0045086 positive regulation of interleukin-2 biosynthesis
GO:0004888 transmembrane receptor activity
GO:0006955 immune response
GO:0050863 regulation of T cell activation
GO:0045058 T cell selection
GO:0042101 T cell receptor complex
GO:0045860 positive regulation of protein kinase activity
GO:0007155 cell adhesion
GO:0008270 zinc ion binding
GO:0042803 protein homodimerization activity
GO:0015026 coreceptor activity

Database cross references


Integrated protein interaction and pathway information

Interacting Partners (HPRD)Experiment
CD44in vitro
CD38in vitro
CTSDin vitro
HLA-DPA1in vivo
FCGR3Ain vitro
IL2RAin vitro
LGALS1in vitro
CXCR4in vivo
PTPRCin vivo
CD53in vitro
CD5in vitro
LCKin vivo
PIK3R1in vitro
CD28in vitro
CD2in vitro
DPP4in vitro
CXCL12in vitro
CCR5in vivo
LATin vivo
IL16in vivo
UNC119in vitro;in vivo
SELLin vitro
PIPin vitro;in vivo
PIK4CAin vitro
CD82in vivo
HLA-DQA2in vitro
SPG21in vivo;yeast 2-hybrid
MARCH4in vitro
CD4in vivo
KCNAB2in vitro
HLA-DQB1in vitro
TNFRSF10Ain vivo
TFRCin vivo

Interacting Partners (NetPath)LCK [3262426 ] UNC119 [14757743 ] LAT [10562325 ]

Interacting Partner (IntAct)Interaction typeDetection method
CCR5 physical interaction coip
ACTB physical interaction molecular sieving

Pathway (KEGG)[Cell adhesion molecules (CAMs)] [Antigen processing and presentation] [Hematopoietic cell lineage] [T cell receptor signaling pathway]

Pathway (CGAP/BioCarta)[Antigen Dependent B Cell Activation ] [Bystander B Cell Activation ] [Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor ] [IL 17 Signaling Pathway ] [IL 5 Signaling Pathway ] [Cytokines and Inflammatory Response ] [Selective expression of chemokine receptors during T-cell polarization ] [NO2-dependent IL 12 Pathway in NK cells ] [Regulation of hematopoiesis by cytokines ] [HIV Induced T Cell Apoptosis ] [Lck and Fyn tyrosine kinases in initiation of TCR Activation ] [T Helper Cell Surface Molecules ] [HIV-1 defeats host-mediated resistance by CEM15 ]

© 2008 National Taiwan Univerisity, Taipei, Taiwan