IDSwiss AccGene NameAliasDescription
1995Q14576ELAVL3HUC; HUCL; PLE21; MGC20653; DKFZp547J036ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
[more aliases]
FunctionA member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

AssociationsTCM-GeneTCM-Gene-Disease

Gene OntologyGO:0007399 nervous system development
GO:0030154 cell differentiation
GO:0003730 mRNA 3'-UTR binding
GO:0000166 nucleotide binding
GO:0003723 RNA binding

Database cross references

STITCHELAVL3

Integrated protein interaction and pathway information

Interacting Partners (HPRD)Experiment
EWSR1yeast 2-hybrid
ELAVL2in vitro;in vivo;yeast 2-hybrid

Interacting Partner (IntAct)Interaction typeDetection method
EWSR1 physical interaction two hybrid pooling


© 2008 National Taiwan Univerisity, Taipei, Taiwan